Publications
Agbavor C, Zimnicka A, Kumar A, George JL, Torres M, Prehna G, Alonzo F 3rd, Durrant JD, Freitag NE, Cahoon LA. The chaperone PrsA2 regulates the secretion, stability, and folding of listeriolysin O during Listeria monocytogenes infection. mBio. 2024 May 29:e0074324. doi: 10.1128/mbio.00743-24.
da Silva RJ, Cabo LF, George JL, Cahoon LA, Yang L, Coyne CB, Boyle JP.The trophoblast surface becomes refractory to adhesion by congenitally transmitted Toxoplasma gondii and Listeria monocytogenes during cytotrophoblast to syncytiotrophoblast development. mSphere0:e00748-23.https://doi.org/10.1128/msphere.00748-23
George JL, Agbavor C, Cabo LF, Cahoon LA. Streptococcus pneumoniae secretion chaperones PrsA, SlrA, and HtrA are required for competence, antibiotic resistance, colonization, and invasive disease. Infect Immun. 2024 Feb 13;92(2):e0049023. doi: 10.1128/iai.00490-23. Epub 2024 Jan 16.
Cahoon LA, Alejandro-Navarreto X, Gururaja AN, Light SH, Alonzo F, Anderson WF, Freitag NE. Listeria monocytogenes two component system PieRS regulates secretion chaperones PrsA1 and PrsA2 and enhances bacterial translocation across the intestine. Mol Microbiol. 2022 Jul 31. doi: 10.1111/mmi.14967.
Ignatov D, Vaitkevicius K, Durand S, Cahoon L, Sandberg SS, Liu X, Kallipolitis BH, Rydén P, Freitag N, Condon C, Johansson J. An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes. Cell Rep. 2020 Mar 24;30(12):4027-4040.
Prister LL, Yin S, Cahoon LA, Seifert HS. Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation. Biochemistry. 2020 Mar 17;59(10):1104-1112.
Prister LL, Ozer EA, Cahoon LA, Seifert HS. Transcriptional initiation of a small RNA, not R-loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae. Mol Microbiol. 2019 Oct;112(4):1219-1234.
Cahoon LA, Freitag NE. The electrifying energy of gut microbes. Nature. 2018 Oct;562(7725):43-44.
Light SH, Cahoon LA, Mahasenan KV, Lee M, Boggess B, Halavaty AS, Mobashery S, Freitag NE, Anderson WF. 2017. Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure 2017 25(2):295-304
Light SH, Cahoon LA, Halavaty AS, Freitag NE, Anderson WF. 2016. Structure to function of an α-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis, Nature Microbiology 2:16202
Cahoon LA, Freitag NE, Prehna G. 2016. A structural comparison of Listeria monocytogenes protein chaperones PrsA1 and PrsA2 reveals molecular features required for virulence, Molecular Microbiology 101(1):42-61
Cahoon LA, Freitag NE. 2015. Identification of Conserved and Species-Specific Functions of the Listeria monocytogenes PrsA2 Secretion Chaperone, Infection and Immunity 83(10):4028-41
Cahoon LA, Freitag NE. 2014. Listeria monocytogenes virulence factor secretion: don’t leave the cell without a chaperone, Frontiers in Cellular and Infection Microbiology 4(13):1-10
Cahoon LA, Manthei KA, Rotman E, Keck JL, Seifert HS. 2013. The Neisseria gonorrhoeae RecQ helicase HRDC domains are essential for efficient binding and unwinding of the pilE guanine quartet structure required for pilin Av. Journal of Bacteriology 195(10):2255-61
da Silva RJ, Cabo LF, George JL, Cahoon LA, Yang L, Coyne CB, Boyle JP.The trophoblast surface becomes refractory to adhesion by congenitally transmitted Toxoplasma gondii and Listeria monocytogenes during cytotrophoblast to syncytiotrophoblast development. mSphere0:e00748-23.https://doi.org/10.1128/msphere.00748-23
George JL, Agbavor C, Cabo LF, Cahoon LA. Streptococcus pneumoniae secretion chaperones PrsA, SlrA, and HtrA are required for competence, antibiotic resistance, colonization, and invasive disease. Infect Immun. 2024 Feb 13;92(2):e0049023. doi: 10.1128/iai.00490-23. Epub 2024 Jan 16.
Cahoon LA, Alejandro-Navarreto X, Gururaja AN, Light SH, Alonzo F, Anderson WF, Freitag NE. Listeria monocytogenes two component system PieRS regulates secretion chaperones PrsA1 and PrsA2 and enhances bacterial translocation across the intestine. Mol Microbiol. 2022 Jul 31. doi: 10.1111/mmi.14967.
Ignatov D, Vaitkevicius K, Durand S, Cahoon L, Sandberg SS, Liu X, Kallipolitis BH, Rydén P, Freitag N, Condon C, Johansson J. An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes. Cell Rep. 2020 Mar 24;30(12):4027-4040.
Prister LL, Yin S, Cahoon LA, Seifert HS. Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation. Biochemistry. 2020 Mar 17;59(10):1104-1112.
Prister LL, Ozer EA, Cahoon LA, Seifert HS. Transcriptional initiation of a small RNA, not R-loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae. Mol Microbiol. 2019 Oct;112(4):1219-1234.
Cahoon LA, Freitag NE. The electrifying energy of gut microbes. Nature. 2018 Oct;562(7725):43-44.
Light SH, Cahoon LA, Mahasenan KV, Lee M, Boggess B, Halavaty AS, Mobashery S, Freitag NE, Anderson WF. 2017. Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity. Structure 2017 25(2):295-304
Light SH, Cahoon LA, Halavaty AS, Freitag NE, Anderson WF. 2016. Structure to function of an α-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis, Nature Microbiology 2:16202
Cahoon LA, Freitag NE, Prehna G. 2016. A structural comparison of Listeria monocytogenes protein chaperones PrsA1 and PrsA2 reveals molecular features required for virulence, Molecular Microbiology 101(1):42-61
Cahoon LA, Freitag NE. 2015. Identification of Conserved and Species-Specific Functions of the Listeria monocytogenes PrsA2 Secretion Chaperone, Infection and Immunity 83(10):4028-41
Cahoon LA, Freitag NE. 2014. Listeria monocytogenes virulence factor secretion: don’t leave the cell without a chaperone, Frontiers in Cellular and Infection Microbiology 4(13):1-10
Cahoon LA, Manthei KA, Rotman E, Keck JL, Seifert HS. 2013. The Neisseria gonorrhoeae RecQ helicase HRDC domains are essential for efficient binding and unwinding of the pilE guanine quartet structure required for pilin Av. Journal of Bacteriology 195(10):2255-61